Bioorganic and Medicinal Chemistry Letters p. 4692 - 4696 (2006)
Update date:2022-08-03
Topics:
Lin, Xiaodong
Rico, Alice C.
Chu, Daniel T.
Carroll, Georgia L.
Barker, Lynn
Shawar, Ribhi
Desai, Manoj C.
Plattner, Jacob J.
Synthesis of C12 des-methyl ketolide is developed featuring an intramolecular epoxide formation/elimination process to establish the C12 stereocenter. These ketolides are potent against several key respiratory pathogens, including er
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