Synthesis and biological activity of derivatives of the marine quinone avarone

DOI: 10.1016/j.ejmech.2009.11.033

Source and publish data:

European Journal of Medicinal Chemistry p. 923 - 929 (2010)

Update date:2022-08-02

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Authors:

Bo?i?, Tatjana

Novakovi?, Irena

Ga?i?, Miroslav J.

Jurani?, Zorica

Stanojkovi?, Tatjana

Tufegd?i?, Srdan

Kljaji?, Zoran

Sladi?, Du?an

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Article abstract of DOI:10.1016/j.ejmech.2009.11.033

Nine alkyl(aryl)thio derivatives of the marine sesquiterpene quinone avarone were synthesized by nucleophilic addition of thiols or thiophenol to avarone. In most cases only one regioisomer was obtained. Their cytotoxic activities, brine shrimp lethality

Full text of DOI:10.1016/j.ejmech.2009.11.033

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