Bioorganic and Medicinal Chemistry Letters p. 1941 - 1944 (1999)
Update date:2022-07-29
Topics:
Sutherland, Andrew
Willis, Christine L.
A series of novel 3-substituted 2-oxobutanoic acids were prepared and incubated with leucine dehydrogenase giving in one case both a kinetic resolution at C-3 and reductive amination of the ketone. This is the first example of an amino acid dehydrogenase
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