Phosphorus, Sulfur and Silicon and the Related Elements p. 511 - 522 (2002)
Update date:2022-08-04
Topics:
Chandramouli
Prasanna
Naveen Kumar
Vijayakumar Reddy
The key step for the synthesis of 7-hydroxy 2,3-diarylsubstituted benzothiophenes 5a-f, by starting from substituted 2-aryl-2-((2-methoxy phenyl)thio)acetophenones 3a-f as an intermediate, consists of a Friedel-Crafts cyclization followed by demethylation by Lewis acids like BF3OEt2 and AlCl3 in DCM.
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