Synthesis and Biological Activity of Some 15-Oxaestranes

DOI: 10.1021/jm00177a026

Source and publish data:

Journal of Medicinal Chemistry p. 329 - 330 (1980)

Update date:2022-08-02

Topics:

Authors:

Rosen, Perry

Boris, Alfred

Oliva, Gloria

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Article abstract of DOI:10.1021/jm00177a026

The estrogenic activity of orally administered 15-oxaestrone was evaluated by the uterotropic assay in rats and was found to be 12 times greater than that of estrone.In addition, several analogues of 15-oxaestrone were prepared and their estrogenic potency was determined.

Full text of DOI:10.1021/jm00177a026

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