Highly sensitive detection of GG mismatched DNA by surfaces immobilized naphthyridine dimer through poly(ethylene oxide) linkers

DOI: 10.1016/j.bmcl.2003.12.079

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Bioorganic and Medicinal Chemistry Letters p. 1105 - 1108 (2004)

Update date:2022-08-03

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Authors:

Nakatani, Kazuhiko

Kobori, Akio

Kumasawa, Hiroyuki

Saito, Isao

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Article abstract of DOI:10.1016/j.bmcl.2003.12.079

Naphthyridine dimer is a unique molecule that strongly, and selectively, binds to the guanine-guanine mismatch in duplex DNA. We have synthesized naphthyridine dimers possessing a different length of poly(ethylene oxide) (PEO) linker, and immobilized them

Full text of DOI:10.1016/j.bmcl.2003.12.079

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