Canadian Journal of Chemistry p. 1660 - 1667 (1994)
Update date:2022-08-05
Topics: Column chromatography NMR spectroscopy Catalytic hydrogenation Mass spectrometry (MS) Nucleophilic substitution Cyclization Deprotection Reductive Amination Solvent Evaporation Enamine Pictet-Spengler reaction Reaction yield Formamide β-carboline
Vohra
Maclean
Pyridines and benzopyridines substituted with trimethylsilylmethyl groups, α or γ to the nitrogen atom, have been found to react with formamides by way of a Peterson reaction to form enamines. Trimethylsilylmethylbenzene behaved similarly. The enamines pr
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