
Journal of Medicinal Chemistry p. 1378 - 1381 (1973)
Update date:2022-08-04
Topics:
Vida
Hooker
Samour
Reinhard
Several metharbital and phenobarbital derivatives were found to possess potent anticonvulsant activity and yet were either devoid of the marked hypnotic effects of the parent compounds or displayed very weak hypnotic activity. Particularly active compounds were the monomethoxymethyl derivative of phenobarbital, the 1 methyl 3 butoxymethyl derivative of phenobarbital, and the 3 methoxymethyl derivative of metharbital.
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Doi:10.1016/S0040-4039(01)89785-9
(1967)Doi:10.1021/ic960187o
(1996)Doi:10.1021/jacs.5b08008
(2015)Doi:10.1021/acscatal.9b03367
(2019)Doi:10.1002/chem.200500175
(2005)Doi:10.1016/S0040-4020(01)92641-9
(1968)