One-pot alkoxymercuriation-bromodemercuriation: A versatile access to 3-alkoxy-2-bromopropanoic esters

Article abstract of DOI:10.1080/00397919308013793

A convenient one-pot methodology for the preparation of 3-alkoxy-2-bromopropanoic esters from alkyl acrylates is described. The use of stoichiometric amounts of alkyl acrylate, alcohol and mercury trifluoroacetate in THF makes this procedure versatile and attractive to achieve building blocks for the synthesis of targeted contrast agents for Magnetic Resonance Imaging.

Full text of DOI:10.1080/00397919308013793

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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One-Pot Alkoxymercuriation-
Bromodemercuriation: A
Versatile Access to 3-Alkoxy-2-
bromopropanoic Esters
Pier Lucio Anelli a , Andrea Beltrami a , Marco Lolli a
& Fulvio Uggeri a
a Research and Development Division , Bracco S.p.A.
Via E. Folli, 50, 20134, Milano, Italy
Published online: 23 Sep 2006.
To cite this article: Pier Lucio Anelli , Andrea Beltrami , Marco Lolli & Fulvio Uggeri
(1993) One-Pot Alkoxymercuriation-Bromodemercuriation: A Versatile Access to 3-
Alkoxy-2-bromopropanoic Esters, Synthetic Communications: An International Journal
for Rapid Communication of Synthetic Organic Chemistry, 23:19, 2639-2645, DOI:
10.1080/00397919308013793
To link to this article: http://dx.doi.org/10.1080/00397919308013793
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