Rigid analogs of indomethacin

DOI: 10.1021/jm00248a005

Source and publish data:

Journal of Medicinal Chemistry p. 167 - 171 (1974)

Update date:2022-08-04

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Authors:

Olson Olson

Wheeler Wheeler

Wells Wells

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Article abstract of DOI:10.1021/jm00248a005

10 Chloro 2 methoxy 5 methyl 7 H pyrrolo [3,2,1 de]phenanthrid 7 one 4 acetic acid and its deschloro analog were synthesized as rigid analogs of indomethacin. The chloro analog was found to be inactive in a standard in vivo guinea pig uv erythema assay.

Full text of DOI:10.1021/jm00248a005

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Product name:{1-[4-Chloro-2-(2,2,2-trifluoro-acetylamino)-benzoyl]-5-methoxy-2-methyl-2,3-dihydro-1H-indol-3-yl}-acetic acid methyl ester

Cas No:51984-02-2

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