A butyrolactone → 1,3-diol strategy for the obtention of Tolypothrix polyethers - Stereoselective synthesis of a key lactone precursor

Article abstract of DOI:10.1002/jlac.199719970804

A novel access to 1,3,5,7,...-polyols is developed. It follows - in the context of the planned synthesis of the natural permethylated 1,3,5,7,9-pentaol 1a from the blue-green alga Tolypothrix conglutinata - the strategy, depicted in Scheme 4. The present