Journal of Heterocyclic Chemistry p. 1887 - 1893 (1996)
Update date:2022-08-05
Topics:
Pinto, Diana C. G. A.
Silva, Artur M. S.
Cavaleiro, Jose A. S.
One-pot syntheses of 5-hydroxy-2-(phenyl or styryl)chromones and the corresponding 6- and 8-monoiodo- and 6,8-diiodochromones have been developed. The procedures involve oxidative cyclization of 2′-benzyloxy-6′-hydroxychalcones and 2′-benzyloxy-6′-hydroxy-2-cinnamylideneacetophenones and electrophilic substitution processes on the chromone moieties; such procedures were also applied to the syntheses of 6,8-dibromochromone derivatives.
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