Tetrahedron Letters p. 2183 - 2186 (1999)
Update date:2022-08-05
Topics:
Frost, Lisa M.
Smith, Julian D.
Berrisford, David J.
A new tandem C-C bond forming process has been developed which utilises silicon-tethered dinucleophiles and acetals under Lewis acid conditions. The reaction incorporates a functionalised five carbon unit into both aromatic and aliphatic acetals, affording acyclic-β-alkoxyhomoallylic alcohols in good yields.
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