Synthesis and platelet-activating factor (PAF)-antagonistic activities of 1,4-disubstituted piperazine derivatives

DOI: 10.1248/cpb.42.541

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 541 - 550 (1994)

Update date:2022-09-26

Topics:

Authors:

Fukushi Fukushi

Mabuchi Mabuchi

Itoh Itoh

Terashita

Nishikawa

Sugihara

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Article abstract of DOI:10.1248/cpb.42.541

During the screening of novel platelet-activating factor (PAF) antagonists, we found that 1-(6-methoxy-3,4-dihydro-2-naphthoyl)-4-(3,4,5- trimethoxybenzyl)piperazine and its 4-(3,4,5-trimethoxybenzoyl)piperazine derivatives (1b, 2b) exerted in vitro and i

Full text of DOI:10.1248/cpb.42.541

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