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Benzoselenazolinone Derivatives Designed To Be Glutathione Peroxidase Mimetics Feature Inhibition of Cyclooxygenase/5-Lipoxygenase Pathways and Anti-inflammatory Activity

DOI: 10.1021/jm00044a011

Source and publish data:

Journal of Medicinal Chemistry p. 2903 - 2911 (1994)

Update date:2022-08-05

Topics:

Authors:

Galet, VincentGalet, Vincent

Bernier, Jean-LucBernier, Jean-Luc

Henichart, Jean-PiereHenichart, Jean-Piere

Lesieur, DanielLesieur, Daniel

Abadie, ClaireAbadie, Claire

et al.et al.

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Article abstract of DOI:10.1021/jm00044a011

Two series of compounds, substituted benzoselenazolinones and their opened analogs, diselenides, were prepared.The diselenides were designed according to the available SAR about glutathione peroxidase mimics and were expected to have activity.An initial s

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Full text of DOI:10.1021/jm00044a011

Products guided by the article

Product name:N,N'-(2,2'-diselanediyl-diphenyl)-bis-carbamic acid diethyl ester

Cas No:524951-85-7

524951-85-7

R&D Labs maybe for 524951-85-7

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