
Tetrahedron Letters p. 2405 - 2408 (1998)
Update date:2022-08-03
Topics:
Albanese, Domenico
Leone, Mario
Penso, Michele
Seminati, Monica
Zenoni, Maurizio
Cephalosporins 1a-d have been selectively hydrogenolysed to their corresponding acids 2a-d without isomerisation of the cephem double-bond using anhydrous ammonium formate or phosphinic acid as catalytic transfer agents in the presence of 10% pd/C.
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