First synthesis of the immunodominant β-galactofuranose-containing tetrasaccharide present in the cell wall of Aspergillus fumigatus

Article abstract of DOI:10.1016/j.carres.2004.10.019

β-Galf-(1→5)-β-Galf-(1→6)-α-Manp-(1→6) -α-Manp, the immunodominant epitope in the cell-wall galactomannan of Aspergillus fumigatus, was synthesized for the first time as its allyl glycoside. The key disaccharide glycosyl donor, 2,3,5,6-tetra-O-benzoyl-β-