
Tetrahedron p. 2493 - 2503 (1983)
Update date:2022-08-02
Topics:
Ghosez
Marchand-Brynaert
Vekemans
et al.
Using Penicillin G as starting material, general methods of synthesis for the 2-oxo-penam skeleton have been established. Compounds 7 represent a new group of strained penicillin derivatives. They can be readily transformed into 2-alkoxy 17 or benzoyloxypenems 18.
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