
Journal of Medicinal Chemistry p. 628 - 631 (1981)
Update date:2022-08-03
Topics:
Baldwin, John J.
Hirschmann, R.
Engelhardt, Edward L.
Ponticello, Gerald S.
Sweet, Charles S.
Scriabine, A.
The aminohydroxypropoxy moiety has been incorporated into the dihydrolutidine class of vasodilators.In the spontaneously hypertensive rat, one of these, (S)-4-<2-methyl-4-<3-(tert-butylamino)-2-hydroxypropoxy>phenyl>-3,5-dicarboethoxy-1,4-dihydrolutidine
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(1944)