Bioorganic and Medicinal Chemistry Letters p. 1432 - 1437 (2007)
Update date:2022-08-02
Topics:
Qiao, Jennifer X.
Cheng, Xuhong
Smallheer, Joanne M.
Galemmo, Robert A.
Drummond, Spencer
Pinto, Donald J.P.
Cheney, Daniel L.
He, Kan
Wong, Pancras C.
Luettgen, Joseph M.
Knabb, Robert M.
Wexler, Ruth R.
Lam, Patrick Y.S.
The synthesis, SAR, pharmacokinetic profile, and modeling studies of both monocyclic and fused pyrazoles containing substituted N-arylpiperidinyl P4 moieties that are potent and selective factor Xa inhibitors will be discussed. Fused pyrazole analog 16a,
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Doi:10.1016/S0022-328X(00)82457-2
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