Silyl modification of biologically active compounds. 3. Organosilicon derivatives of aminoalcohols in the series of tetrahydroquinoline, tetrahydroisoquinoline, and tetrahydrosilaisoquinoline

Article abstract of DOI:10.1007/BF01164867

The N-(2′-hydroxyethyl)-1,2,3,4-tetrahydroquinoline, -isoquinoline, and -silaisoquinoline, and their trimethyl-and triethylsilyl derivatives and the corresponding methiodides were synthesized. The acute toxicity and psychotropic activity of the compounds synthesized were studied. 1997 Plenum Publishing Corporation.