Journal of Medicinal Chemistry p. 1508 - 1511 (1977)
Update date:2022-08-05
Topics:
Lee
Michaels
Zaugg
Dren
Plotnikoff
Young
8-(1,2-Dimethylheptyl)- and 8-[5-(4-fluorophenyl)-2-pentyl]-10-hydroxy- 5,5-dimethyl-5H-[1]benzopyrano[4,3-c]pyridines (2a and 2b), their phenolic ester and ether derivatives, and their N-oxides were synthesized and evaluated in various CNS pharmacological tests in animals. 2a was found to be the most potent compound.
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