C.-G. Huang et al. / Tetrahedron Letters 43 (2002) 2721–2723
2723
Acknowledgements
J=14.5 Hz, 1H), 4.38 (d, J=14.5 Hz, 1H), 3.33 (dd,
J=5.5, 12.5 Hz, 1H), 3.09 (dd, J=5.5, 12.5 Hz, 1H),
2.68–2.6 (m, 2H), 2.50 (dd, J=7.5, 12 Hz, 1H); 1c: 1H
NMR (500 MHz, CDCl3): l 7.35–7.26 (m, 5H), 6.48 (dd,
J=4, 10 Hz, 1H), 5.99 (dd, J=1.5, 10 Hz, 1H), 5.65–5.56
(m, 1H), 5.00 (d, J=9.5 Hz, 1H), 4.85 (d, J=17.5 Hz, 1H),
4.65 (d, J=14 Hz, 1H), 4.54 (d, J=14 Hz, 1H), 3.34 (dd,
J=6, 12.5 Hz, 1H), 3.13 (dd, J=8, 12.5 Hz, 1H), 2.48–
The authors would like to thank the National Science
Council of the Republic of China for financial support.
References
1
2.46 (m, 1H), 2.15–2.00 (m, 2H); 1d: H NMR (500 MHz,
CDCl3): l 7.34–7.26 (m, 5H), 6.41 (dd, J=3.5, 10Hz, 1H),
5.94 (dd, J=2.10 Hz, 1H) 4.61 (s, 2H), 3.31 (dd, J=6, 12
Hz, 1H), 3.03 (dd, J=9.5, 12 Hz, 1H), 2.59–2.57 (m, 1H),
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1
1.00 (d, J=7.5 Hz, 3H); 1f: H NMR (500 MHz, CDCl3):
l 6.82–6.77 (m, 3H), 6.47 (dd, J=3.5 Hz, 10 Hz, 1H), 6.01
(dd, J=1.5, 10 Hz, 1H), 3.90–3.82 (m, 6H), 3.71–3.65 (m,
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3.11 (dd, J=9, 12.5 Hz, 1H), 2.84 (t, J=7.5 Hz, 2H),
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0.90 (t, J=8 Hz, 3H).
1
8. Selected spectral data of 7d: H NMR (500 MHz, CDCl3):
l 7.66–7.62 (m, 3H), 7.48 (t, J=7 Hz, 2H), 7.33–7.25 (m,
5H), 5.00 (d, J=14 Hz, 1H), 4.88 (d, J=14 Hz, 1H), 4.12
(dd, J=2, 6.5 Hz, 1H), 3.36–3.31 (m, 1H), 2.89–2.85 (m,
1H), 2.07–2.00 (m, 1H), 1.33 (d, J=7 Hz, 3H); 8d: 1H
NMR (500 MHz, CDCl3): l 7.98 (d, J=7.5 Hz, 2H), 7.65
(t, J=7.5 Hz, 1H), 7.58–7.54 (m, 2H), 7.35–7.25 (m, 3H),
7.16 (d, J=7.5 Hz, 2H), 4.60 (d, J=14.5 Hz, 1H), 4.47 (d,
J=14.5 Hz, 1H), 4.19 (dd, J=7.5, 11 Hz, 1H), 3.09–3.05
(m, 1H), 2.99 (t, J=12 Hz, 1H), 2.49–2.44 (m, 1H),
2.14–1.95 (m, 2H), 1.03 (d, J=6.5 Hz, 3H).
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1
7. Selected spectral data of 1b: H NMR (500 MHz, CDCl3):
l 7.36–7.19 (m, 8H), 6.87 (d, J=6.5 Hz, 1H), 6.48 (dd,
J=3.5, 10 Hz, 1H), 6.00 (d, J=10 Hz, 1H), 4.80 (d,