A highly enantioselective Lewis basic organocatalyst for reduction of N-aryl imines with unprecedented substrate spectrum

DOI: 10.1021/ol060112g

Source and publish data:

Organic Letters p. 999 - 1001 (2006)

Update date:2022-08-03

Topics:

Authors:

Wang, Zhouyu

Ye, Xiaoxia

Wei, Siyu

Wu, Pengcheng

Zhang, Anjiang

Sun, Jian

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Article abstract of DOI:10.1021/ol060112g

L-Pipecolinic acid derived formamides have been developed as highly efficient and enantioselective Lewis basic organocatalysts for the reduction of N-aryl imines with trichlorosilane. Catalyst 4b afforded high isolated yields (up to 98%) and enantioselect

Full text of DOI:10.1021/ol060112g

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