Antiandrogenic Activity of a Series if Des-A-Steroid Derivatives

DOI: 10.1021/jm00150a009

Source and publish data:

Journal of Medicinal Chemistry p. 1796 - 1803 (1985)

Update date:2022-07-30

Topics:

Authors:

Morales-Alanis, Hilda

Brienne, Marie-Josephe

Jacques, Jean

Bouton, Marie-Madeleine

Nedelec, Lucien

et al. et al.

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Article abstract of DOI:10.1021/jm00150a009

In the search for new antiandrogens, a number of des-A-steroids were prepared by condensation of Grignard reagents with lactone 3.From the resulting key intermediates 5, various structural modifications were performed such as the introduction of an additi

Full text of DOI:10.1021/jm00150a009

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