Journal of Medicinal Chemistry p. 1796 - 1803 (1985)
Update date:2022-07-30
Topics:
Morales-Alanis, Hilda
Brienne, Marie-Josephe
Jacques, Jean
Bouton, Marie-Madeleine
Nedelec, Lucien
et al.
In the search for new antiandrogens, a number of des-A-steroids were prepared by condensation of Grignard reagents with lactone 3.From the resulting key intermediates 5, various structural modifications were performed such as the introduction of an additi
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