Tetrahedron p. 2269 - 2274 (1998)
Update date:2022-07-30
Topics:
Bushell, Simon M.
Crump, J. Paul
Lawrence, Nicholas J.
Pineau, Guillaume
The synthesis of aminoglutethimide via a one-pot coupling of nitrobenzene, ethyl 2-chlorobutyrate and 3-bromopropionitrile has been achieved via a process involving sequential vicarious nucleophilic aromatic substitution and alkylation.
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Doi:10.1246/bcsj.53.1652
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