Enantioselective deprotonation of cyclohexene oxide to (R)-2-cyclohexen- 1-ol

Article abstract of DOI:10.1080/00397919408011752

The reaction of cyclohexene oxide with homochiral lithium amides, prepared from (S)-phenylglycine and (S)-valine has been studied and (R)-2-cyclohexen- 1-ol 3 was prepared in a maximum of 72% ee. The optical purity was determined by ¹H NMR measurement of the α-methoxy-α-(trifluoromethyl)phenyl acetic acid (MTPA) derivative of the corresponding alcohol.

Full text of DOI:10.1080/00397919408011752

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Synthetic Communications: An
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Enantioselective Deprotonation
of Cyclohexene Oxide to (R)-2-
Cyclohexen-1-ol
Debnath Bhuniya a & Vinod K. Singh a
a Department of Chemistry , Indian Institute of
Technology , Kanpur, India , 208 016
Published online: 23 Sep 2006.
To cite this article: Debnath Bhuniya & Vinod K. Singh (1994) Enantioselective
Deprotonation of Cyclohexene Oxide to (R)-2-Cyclohexen-1-ol, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic
Organic Chemistry, 24:10, 1475-1481, DOI: 10.1080/00397919408011752
To link to this article: http://dx.doi.org/10.1080/00397919408011752
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