Synthesis of hexahydrocyclopenta[ ij ]isoquinolines as a new class of dopaminergic agents

Article abstract of DOI:10.1016/j.ejmech.2014.11.009

In this study, we have described the synthesis of the tricyclic 1,2,3,7,8,8a-hexahydrocyclopenta [ij]isoquinoline (HCPIQ). Herein, six differently substituted 5,6-dioxygenated-7-phenyl-HCPIQs have been synthesized using a new methodology via (E)-1-styryl-