Biaryl hydroxy aldehydes as intermediates in the metal-assisted atropo- enantioselective reduction of biaryl lactones: Structures and aldehyde- lactol equilibria

Article abstract of DOI:10.1016/S0040-4020(98)00618-8

The synthesis of substituted 1-(2'-hydroxyphenyl)naphthalene-2- carbaldehydes 4 and 6-alkoxy -6H-pyrans 7 and 8, analogs of the postulated metallated intermediates in the atropo-enantioselective ring cleavage of configuratively unstable biaryl lactones 2,