Tetrahedron Letters p. 3115 - 3118 (1997)
Update date:2022-08-04
Topics:
Teresa
Carvalho
Lobo, Ana M.
Branco, Paula S.
Prabhakar, Sundaresan
1-Aryl-2-acyl-2-cyanohydrazines undergo smooth thermal rearrangements to provide 2-aminoacylbenzimidazoles in excellent yields. A short synthesis of the highly mutagenic dietary amine, IQ, is reported.
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