A non ozone approach to enol azetidinones: Synthetic precursors to β-lactam antibiotics

Article abstract of DOI:10.1055/s-1993-25850

The enol-substituted azetidininones (diphenylmethyl 2-[(3R,4R)-4-(2-benzothiazolyldithio)-2-oxo-3-(phenoxyacetylamino)-1- azetidinyl]-3-hydroxy-2-butenoate and derivatives) are valuable intermediates in the synthesis of a variety of cephalosporins. A comb