Journal of Medicinal Chemistry p. 1797 - 1801 (1993)
Update date:2022-08-05
Topics: Synthesis Evaluation NMR spectroscopy Catalyst Reaction mixture Antitumor Activity Cell viability assay
Huang, Zhen-Dong
Chen, Ying-Nan
Menon, Krishna
Teicher, Beverly A.
A series of 4,5-diamino-substituted-1,2-benzoquinones were prepared from catechol and the corresponding secondary amines in high yield in a single step using copper complex formation to stabilize the intermediate.The cytotoxicity of the products under var
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