Nucleosides, nucleotides and nucleic acids p. 671 - 690 (2004)
Update date:2022-07-30
Topics:
Kohgo, Satoru
Yamada, Kohei
Kitano, Kenji
Iwai, Yuko
Sakata, Shinji
Ashida, Noriyuki
Hayakawa, Hiroyuki
Nameki, Daisuke
Kodama, Eiichi
Matsuoka, Masao
Mitsuya, Hiroaki
Ohrui, Hiroshi
Some 4′-C-ethynyl-2′-deoxy purine nucleosides showed the most potent anti-HIV activity among the series of 4′-C-substituted 2′-deoxynucleosides whose 4′-C-substituents were methyl, ethyl, ethynyl and so on. Our hypothesis is that the smaller the substitue
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