A second-generation 99mtechnetium single photon emission computed tomography agent that provides in vivo images of the dopamine transporter in primate brain

DOI: 10.1021/jm0301484

Source and publish data:

Journal of Medicinal Chemistry p. 3483 - 3496 (2003)

Update date:2022-08-04

Topics:

Authors:

Meltzer, Peter C.

Blundell, Paul

Zona, Thomas

Yang, Lihua

Huang, Hong

Bonab, Ali A.

Livni, Eli

Fischman, Alan

Madras, Bertha K.

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Article abstract of DOI:10.1021/jm0301484

The dopamine transporter (DAT), located presynaptically on dopamine neurons, provides a marker for Parkinson's disease (Pd) and attention deficit hyperactivity disorder (ADHD). In ADHD, DAT density levels are elevated, while in Pd these levels are deplete

Full text of DOI:10.1021/jm0301484

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