Synthesis of Macrocyclic Propargylic Alcohols by Ene-Type Cyclization of Unsaturated Acetylenic Aldehydes

DOI: 10.1021/jo00036a002

Source and publish data:

Journal of Organic Chemistry p. 2766 - 2768 (1992)

Update date:2022-09-26

Topics:

Authors:

Marshall, James A.

Andersen, Marc W.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00036a002

Ene type cyclizations of ynals 6, 21, and 30 can be effected by EtAlCl2 in CH2Cl2 at -78 deg C to afford 14- and 12-membered homoallylic propargylic alcohols in 66-89 percent yield.

Full text of DOI:10.1021/jo00036a002

Products guided by the article

Product name:(+/-)-mukulol

Cas No:59686-15-6

R&D Labs maybe for 59686-15-6

Anhui Sholon New Material Technology Co., Ltd.

website:http://www.sholonchem.com

Contact:+86-550-5261666

Address:4/F Block B, Beijing Chemical Building.No.520 Tianrun Road ,Science & Education Town Wujin District, Changzhou City Jiangsu Province
Zhejiang Haizhou Pharmaceutical Co., Ltd.

website:https://www.haizhoupharma.com/

Contact:+86-576-88221016

Address:No. 19, Donghai 5th Avenue, Yanhai Industrial Zone, Linhai, Zhejiang, China
Huangshan Violet Biological Technology Co., Ltd

Contact:+86-559-2335676

Address:16-201 JinShanYuan,JiangNan New City,TunXi District,HuangShan City,AnHui Province,China
Nowa pharmaceuticals Co., LTD

Contact:86-512-69362780,69362785

Address:No.69 Weixin Road,Weiting Town,Suzhou Industrial Park
Changsha Botaniex Inc.

Contact:(86) 731 88718666

Address:Room 1222, Unit 4, Building B, Shangcheng, No.47, Kaiyuan East Road.

Relevant to this article

Modification of the 5' position of purine nucleosides. 1. Synthesis and biological properties of alkyladenosine-5'-carboxylates.

Doi:10.1021/jm00232a003
(1976)
Stereoselective synthesis of L-733,060

Doi:10.1016/S0040-4039(02)02772-7
(2003)
Regioselective ortho Amination of Coordinated 2-(Arylazo)pyridine. Isolation of Monoradical Palladium Complexes of a New Series of Azo-Aromatic Pincer Ligands

Doi:10.1021/acs.inorgchem.5b02110
(2015)
The synthesis of 2'-O-methyl G-clamp containing oligonucleotides and their inhibition of the HIV-1 Tat-TAR interaction.

Doi:10.1081/NCN-120022850
(2003)
Reaction of 2,4,6-trialkylpyrimidine 1,3-dioxides with electrophilic reagents

Doi:10.1007/BF00507100
(1981)
Controllable Rh(III)-Catalyzed C-H Arylation and Dealcoholization: Access to Biphenyl-2-carbonitriles and Biphenyl-2-carbimidates

Doi:10.1021/acs.orglett.8b02915
(2018)

Article Doi