Synthesis of Macrocyclic Propargylic Alcohols by Ene-Type Cyclization of Unsaturated Acetylenic Aldehydes

DOI: 10.1021/jo00036a002

Source and publish data:

Journal of Organic Chemistry p. 2766 - 2768 (1992)

Update date:2022-09-26

Topics:

Authors:

Marshall, James A.

Andersen, Marc W.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00036a002

Ene type cyclizations of ynals 6, 21, and 30 can be effected by EtAlCl2 in CH2Cl2 at -78 deg C to afford 14- and 12-membered homoallylic propargylic alcohols in 66-89 percent yield.

Full text of DOI:10.1021/jo00036a002

Products guided by the article

Product name:(+/-)-mukulol

Cas No:59686-15-6

R&D Labs maybe for 59686-15-6

Jiangsu Fengshan Group Co., Ltd.

Contact:86-25-86558671

Address:1903,Central International Mansion 105-6 North Zhongshan Road, Nanjing, China
Suzhou JMS Chemical Co., Ltd.

Contact:+86-15995924277

Address:WuZhongOu suzhou new south road 89
Winchem Industrial Co. Ltd.(expird)

Contact:86-574-83851061 86-574-87083208

Address:Room 905, No.3 Building,East Business Center, 456 Xingning Road, Ningbo City,China
Zhuhai Rundu Pharmaceutical co.,Ltd

Contact:+86-756-7630755

Address:No.6,North Airport Road,Sanzao Town,Jinwan District
HAINAN JINYING IMPORT AND EXPORT CO. LTD

Contact:+86-898-32875423

Address:A SECTION 19TH FL, TIMES SQUARE, NO.2 GUO MAO AVENUE HAIKOU, HAINAN, P. R. OF CHINA

Relevant to this article

Modification of the 5' position of purine nucleosides. 1. Synthesis and biological properties of alkyladenosine-5'-carboxylates.

Doi:10.1021/jm00232a003
(1976)
Stereoselective synthesis of L-733,060

Doi:10.1016/S0040-4039(02)02772-7
(2003)
Regioselective ortho Amination of Coordinated 2-(Arylazo)pyridine. Isolation of Monoradical Palladium Complexes of a New Series of Azo-Aromatic Pincer Ligands

Doi:10.1021/acs.inorgchem.5b02110
(2015)
The synthesis of 2'-O-methyl G-clamp containing oligonucleotides and their inhibition of the HIV-1 Tat-TAR interaction.

Doi:10.1081/NCN-120022850
(2003)
Reaction of 2,4,6-trialkylpyrimidine 1,3-dioxides with electrophilic reagents

Doi:10.1007/BF00507100
(1981)
Controllable Rh(III)-Catalyzed C-H Arylation and Dealcoholization: Access to Biphenyl-2-carbonitriles and Biphenyl-2-carbimidates

Doi:10.1021/acs.orglett.8b02915
(2018)

Article Doi