Journal of Medicinal Chemistry p. 1180,1182 (1976)
Update date:2022-09-26
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Prasad et al.
A series of esters of adenosine-5'-carboxylic acid has been prepared. Most of the compounds were nontoxic, causing prolonged increases in coronary sinus PO2 when administered to anesthetized dogs; the ethyl ester was most active. Nitrosation and oxidation of the ethyl ester 12 gave respectively inactive inosine ethyl ester 30 and the fairly active N1-oxide ethyl ester 29.
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(1980)Doi:10.1016/S0040-4039(00)82099-7
(1988)Doi:10.1002/cbic.202000658
(2021)Doi:10.1055/s-1981-29354
(1981)Doi:10.1021/ja02218a013
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