Synthesis and structure-activity relationships of 1-substituted 4-(1,2-diphenylethyl)piperazine derivatives having narcotic agonist and antagonist activity

DOI: 10.1021/jm00393a017

Source and publish data:

Journal of Medicinal Chemistry p. 1779 - 1787 (1987)

Update date:2022-08-05

Topics:

Authors:

Natsuka Natsuka

Nakamura

Nishikawa

Negoro Negoro

Uno Uno

Nishimura

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00393a017

Racemates and enantiomers of 1-substituted 4-[2-(3-hydroxyphenyl)-1-phenylethyl]piperazine derivatives (3-18) were synthesized, and their analgesic and other pharmacological activities and structure-activity relationships were investigated. The S-(+) enan

Full text of DOI:10.1021/jm00393a017

Products guided by the article

Product name:Piperazine, 1-[2-(3-methoxyphenyl)-1-phenylethyl]-, dihydrochloride

Cas No:61311-63-5

R&D Labs maybe for 61311-63-5

Hangzhou Hysen Pharma co.,Ltd.

website:http://www.hysenpharma.cn/

Contact:0086-571-88298791

Address:#701,Gudun Road Hangzhou
HANGZHOU FOREWIN PHARMA CO., LTD

Contact:+86-571-89053961

Address:hangzhou
CHENGDU CHENLV HERB CO.,LTD

Contact:+86-28-88523492

Address:714rooms of Time Square, Pujiang County
ZhangJiaGang YaRui Chemical Co.,Ltd.

Contact:0512-58360968

Address:China JiangSu Province Zhang Jia Gang City YangShe Oriental Plaza Building 10 B307
ANTAI BIO-TECH CO LTD

website:http://www.antaibio.com

Contact:0086-21-65663057

Address:Room 2108, Building 2，No. 489 Zhengli Road，200433

Relevant to this article

Novel cyclohexyl-amides as potent antibacterials targeting bacterial type IIA topoisomerases

Doi:10.1016/j.bmcl.2011.09.114
(2011)
Stereoselective synthesis of (E) α- Fluorovinylphosphonates from α,α-difluorophosphonates

Doi:10.1055/s-0030-1259294
(2011)
Dehydrogenation of ketones by pincer-ligated iridium: Formation and reactivity of novel enone complexes

Doi:10.1016/j.ica.2010.11.016
(2011)
Chiral thiols: The assignment of their absolute configuration by ¹H NMR

Doi:10.1021/ol7022196
(2007)
Potential Antimitotic Agents. Synthesis of Some Ethyl Benzopyrazin-7-ylcarbamates, Ethyl Pyrido<3,4-b>pyrazin-7-ylcarbamates, and Ethyl Pyrido<3,4-e>-as-triazin-7-ylcarbamates

Doi:10.1021/jm00173a021
(1990)
Synthesis of substituted azaindenes: Synthesis of new pyrazolo-[1,5-a]pyrimidine derivatives

Doi:10.1246/bcsj.63.1854
(1990)

Article Doi