
Journal of Medicinal Chemistry p. 1942 - 1953 (1992)
Update date:2022-08-04
Topics:
Carling, Robert W.
Leeson, Paul D.
Moseley, Angela M.
Baker, Raymond
Foster, Alan C.
et al.
2-Carboxy-1,2,3,4-tetrahydroquinoline derivatives, derived from kynurenic acid, have been synthesized and evaluated for in vitro antagonist activity at the glycine site on the NMDA receptor. 2,3-Dihydrokynurenic acids show reduced potency relative to the
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