Tetrahedron Letters p. 4217 - 4220 (1996)
Update date:2022-08-05
Topics:
Harwood, Laurence M.
Tucker, Toby T.
Angell, Richard
Finch, Harry
Reaction of dimethyl acetylenedicarboxylate with 2-aminoalcohols possessing a primary amino group gives 3- methoxycarbonylmethylidinemorpholin-2-ones 5. Subsequent ozonolysis furnishes morpholin-2,3-diones 1 in excellent yields.
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