N-(2,4,5-trihydroxyphenethyl)normetazocine, a potential irreversible inhibitor of the narcotic receptor

Article abstract of DOI:10.1021/jm00215a011

The reaction of N-(2,4,5-tribenzyloxyphenyl)ethyl methanesulfonate, prepared in a seven-step sequence, with normetazocine followed by hydrogenolysis of the benzyloxy-protecting groups, gave N-(2,4,5-trihydroxyphenethyl)normetazocine. This compound was pre