2,6-Quinolinyl derivatives as potent VLA-4 antagonists

DOI: 10.1016/j.bmcl.2006.09.069

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 142 - 146 (2007)

Update date:2022-08-04

Topics:

Authors:

Lassoie, Marie-Agnes

Broeders, Fabienne

Collart, Philippe

Defrere, Laurent

de Laveleye-Defais, Francoise

Demaude, Thierry

Gassama, Abdoulaye

Guillaumet, Gerald

Hayez, Jean-Claude

Kiss, Laszlo

Knerr, Laurent

Nicolas, Jean-Marie

Norsikian, Stephanie

Quere, Luc

Routier, Sylvain

Verbois, Valerie

Provins, Laurent

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Article abstract of DOI:10.1016/j.bmcl.2006.09.069

A new series of 2,6-quinolinyl derivatives was prepared leading to potent low nanomolar VLA-4/VCAM-1 antagonists.

Full text of DOI:10.1016/j.bmcl.2006.09.069

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