Tetrahedron p. 209 - 217 (1982)
Update date:2022-08-04
Topics:
Wijnberg, B. P.
Speckamp, W. N.
Oostveen, A. R. C.
Stereocontrolled NaBH4/H+-reduction of 3,4-cis-disubstituted N-alkenyl imides 1-5 leads to secondary hydroxylactams.Tertiary hydroxylactams are formed via addition of MeMgCl to imides 2 and 4.HCOOH-Cyclisation of the hydroxylactams affords polycyclic piperidines through stereoselective α-acyliminium ring closure.Concomitant synchronous and stepwise cyclisation pathways are operative in the anti-periplanar addition of tertiary α-acyliminium ions to Me substituted olefins 8c and 11c.
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Doi:10.1016/S0968-0896(03)00063-4
(2003)Doi:10.1023/A:1012357001662
(2001)Doi:10.1016/j.tet.2005.03.064
(2005)Doi:10.1039/b303618a
(2003)Doi:10.1016/S0957-4166(03)00247-7
(2003)Doi:10.1002/ejoc.200300218
(2003)
