Letters in Organic Chemistry p. 276 - 279 (2012)
Update date:2022-07-30
Topics:
Mei, Yi Cheng
Yang, Bao Wei
Chen, Wei
Huang, Dan Dan
Li, Ying
Deng, Xin
Liu, Bao Ming
Wang, Jing Jie
Qian, Hai
Huang, Wen Long
Abstract: This paper reports a novel approach to synthesize pazopanib. In our synthetic route, the potently mutagenic alkylating agents such as dimethyl sulfate and methyl iodide are avoided. A novel regioselective methylation of the 2- position of 3-methyl-6-nitro-1H-indazole was reported. This novel route is one step shorter than the previously reported route.
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Doi:10.1080/00397910701863608
(2008)Doi:10.1021/je00045a037
(1986)Doi:10.1007/s00706-007-0676-4
(2007)Doi:10.1021/ol800471b
(2008)Doi:10.1039/c39850001638
(1985)Doi:10.1021/jo01266a067
(1968)
