Regioselective modification of Lysine's amino groups by proteases.

DOI: 10.1271/bbb1961.55.3067

Source and publish data:

Agricultural and biological chemistry p. 3067 - 3073 (1991)

Update date:2022-08-05

Topics:

Authors:

Kitaguchi

Ono Ono

Itoh Itoh

Klibanov

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1271/bbb1961.55.3067

The regioselectivity of six serine proteases for the amino groups of lysine was investigated. alpha-Chymotrypsin showed a preference for the alpha-amino group, although the selectivity can be varied 10-fold depending on the reaction medium. Subtilisin Car

Full text of DOI:10.1271/bbb1961.55.3067

Products guided by the article

Product name:Z-Phe-Lys(Z)-O-tert-Bu

Cas No:63629-31-2

R&D Labs maybe for 63629-31-2

Changsha Yonta Industry Co., Ltd.

Contact:+ 86-731-8535 2228

Address:Rm.1717, North Bldg., No.368, East 2nd Ring Road(2nd Section)
TIC Gums, Inc.

Contact:410-273-7300; 800-221-3953

Address:4609 Richlynn Dr., PO Box 369, Belcamp, MD, 21017-0369, USA
Jiangsu Dacheng Pharmaceutical and Chemical Co.,Ltd

Contact:+86-0517-87036900

Address:Chuzhou Chemical park, Huai'an, Jiangsu Province
SHANDONG CREDAGRI CHEMICAL CO., LTD.

Contact:+86-531-88872050

Address:ROOM 601A, BUILDING 2, SHUNTAI SQUARE, NO. 2000 SHUNHUA ROAD, HI-TECH DEVELOPMENT ZONE, JINAN, CHINA.
CHEM PLUS

Contact:0027-717-456976

Address:2ND FLOOR, 325 VAUSE ROAD, OVERPORT, 4001, SOUTH AFRICA

Relevant to this article

Synthesis of an o-nitrobenzyl attached A₁ adenosine receptor antagonist, a prodrug approach

Doi:10.1081/SCC-120021980
(2003)
An investigation of the Lewis acid mediated 1,3-dipolar cycloaddition between N-benzyl-C-(2-pyridyl)nitrone and allylic alcohol. Direct entry to isoxazolidinyl C-nucleosides

Doi:10.1039/b304112c
(2003)
Doi:10.1021/jm00220a008
(1977)
Mixed κ agonists and μ agonists/antagonists as potential pharmacotherapeutics for cocaine abuse: Synthesis and opioid receptor binding affinity of N-substituted derivatives of morphinan

Doi:10.1016/S0960-894X(01)00543-1
(2001)
Synthesis of β-Chloroimines

Doi:10.1055/s-1986-31508
(1986)
Doi:10.1021/jo00917a023
(1974)

Article Doi