An efficient and stereoselective synthesis of 3,4,6-tri-O-acetyl-α-D-glucopyranose 1,2-(exo-alkyl orthoacetates)

Article abstract of DOI:10.1016/S0040-4039(00)84932-1

The treatment of acetobromoglucose with N,N-dimethylformamide dialkyl acetals in the presence of tetra-n-butylammonium bromide affords the corresponding 1,2-exo-alkyl orthoacetates in a pure form and in almost quantitative yields.