Tetrahedron p. 3549 - 3553 (2016)
Update date:2022-08-04
Topics:
Brackett, Christopher M.
Furlani, Robert E.
Anderson, Ryan G.
Krishnamurthy, Aparna
Melander, Roberta J.
Moskowitz, Samuel M.
Ernst, Robert K.
Melander, Christian
We recently reported a 2-aminoimidazole-based antibiotic adjuvant that reverses colistin resistance in two species of Gram-negative bacteria. Mechanistic studies in Acinetobacter baumannii demonstrated that this compound downregulated the PmrAB two-compon
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