Study of the Lewis acid-promoted addition of silylenol ethers to imines derived from glyceraldehyde

DOI: 10.1016/j.tetlet.2003.10.027

Source and publish data:

Tetrahedron Letters p. 9189 - 9192 (2003)

Update date:2022-08-03

Topics:

Authors:

Badorrey, Ramon

Cativiela, Carlos

Diaz-de-Villegas, Maria D.

Galvez, Jose A.

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Article abstract of DOI:10.1016/j.tetlet.2003.10.027

Chiral N-benzylimines derived from D-glyceraldehyde undergo Lewis acid-promoted asymmetric Mannich reactions with O-methyl-O-trimethylsilyl dimethylketeneacetal to give β-amino acid esters in good yields and with excellent diastereoselectivities.

Full text of DOI:10.1016/j.tetlet.2003.10.027

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