
Heterocycles p. 745 - 755 (1997)
Update date:2022-08-03
Topics:
Miyashita, Akira
Nagasaki, Izuru
Kawano, Akiko
Suzuki, Yumiko
Iwamoto, Ken-Ichi
Higashino, Takeo
Mercaptoheteroarenes (1) underwent electrophilic cyanation with p-toluenesulfonyl cyanide (TsCN) in THF in the presence of NaH to give the corresponding thiocyanatoheteroarenes (2) in moderate to good yields. In DMF, tosylheteroarenes (4) were formed by substitution with p-toluenesulfinate ion through thiocyanatoheteroarenes (2).
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