Synthesis of 10-cyanoverticillene and its reactions directed toward the verticillol synthesis

Article abstract of DOI:10.1246/bcsj.69.221

Directed toward the synthesis of verticillols, 10-cyanoverticillene 8 was settled as a key intermediate. Bond formation of cyano chloride 7 possessing secoverticillane skeleton to the key intermediate 8 with LiN(TMS)₂ at 60°C proceeded smoothly