A new synthesis of α-amino acid derivatives by reaction of N-acyl-α-triphenylphosphonio-glycinates with carbon nucleophiles

Article abstract of DOI:10.1080/10426500008045231

Recently described¹, easily accessible N-acyl-α-triphenylphosphonioglycinates react smoothly with activated carbonyl compounds or enamines in the presence of a base (DBU or Et₃N) yielding the corresponding α-functionalized glycine derivatives.

Full text of DOI:10.1080/10426500008045231

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Phosphorus, Sulfur, and Silicon
and the Related Elements
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A NEW SYNTHESIS OF α-
AMINO ACID DERIVATIVES
BY REACTION OF N-ACYL-α-
TRIPHENYLPHOSPHOSPHONIO-
GLYCINATES WITH CARBON
NUCLEOPHILES
Roman Mazurkiewicz a & Miroslawa Grymel a
a Institute of Organic Chemistry and Technology,
The Silesian Technical University, Krzywoustego 4,
44-100, Gliwice, Poland
Version of record first published: 27 Oct 2006.
To cite this article: Roman Mazurkiewicz & Miroslawa Grymel (2000): A
NEW SYNTHESIS OF α-AMINO ACID DERIVATIVES BY REACTION OF N-ACYL-α-
TRIPHENYLPHOSPHOSPHONIO-GLYCINATES WITH CARBON NUCLEOPHILES, Phosphorus,
Sulfur, and Silicon and the Related Elements, 164:1, 33-43
To link to this article: http://dx.doi.org/10.1080/10426500008045231
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